Metal-containing Coordination Complexes (MCCs): Assessment of Biological Activity with Helicobacter pylori Caused Gastric Ulcer

The ulcer is a vital disease that unfavorably affects human health globally. Helicobacter pylori, reason forhave an antibacterial effect against ulcers and some stomach disorders, live on using the urease enzyme induces condition to occur. Metal coordination complexes (MCC) are used in numerous industrial areas field. Cyanide bridged metal also applied several places. In current study, characteristic of (C1), [Ni(bishydeten)2Ag(CN)2][Ag(CN)2].H2O), (C2), ([Ni(hydeten)2Ag(CN)2][Ag(CN)2], MCC were analyzed by disk diffusion broth dilution inhibition assays performed. As result both tests, C1 C2 observed provide favorable effects. synthesized compounds have effective inhibitory potential with IC50 value between 26.65±1.21 12.37±0.87 µM for urease.